Radiobiology of Large Animals

Abstract

A review has been completed of all experiments concerned with radiation-induced lethality in sheep and conducted by the Naval Radiological Defense Laboratory and/or the Stanford Research Institute under the auspices of the Defense Civil Preparedness Agency. After consideration of a series of experiments involving sheep exposed at various continuous, intermittent, or combined irradiation schedules at dose rates of 4 R/hr or less, it appears that the major factor determining mortality in such experiments is the average dose per day over the entire exposure period, and not the specific dose rate during the irradiation itself. A mathematical model has been developed that describes the dynamics of injury and repair as a function of daily average dose rate.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1972
Accession Number
AD0752049

Entities

People

  • David C. Jones
  • John S. Krebs

Organizations

  • SRI International

Tags

DTIC Thesaurus Topics

  • Animals
  • Biological Sciences
  • Bone Marrow
  • Cell Count
  • Cells
  • Confidence Limits
  • Dose Rate
  • Gamma Rays
  • Ionizing Radiation
  • Laboratory Animals
  • Mathematical Analysis
  • Plastic Explosives
  • Radiation
  • Radiation Hazards
  • Radiation Injuries
  • Stem Cells
  • X Rays

Fields of Study

  • Physics

Readers

  • Mathematics or Statistics
  • Nuclear and Radiation Engineering.
  • Technical Research and Report Writing.