The Phenomenon of Hybrid Ribonucleoprotein Complexes ('Pseudoviruses') Formation

Abstract

During reproduction of some RNA viruses or after exposure of the infectious RNA isolated from the virions with various cytoplasmatic fractions of the animal cells the formation of hibrid RNP-complexes ('pseudoviruses') is recorded. These present characteristic biological and physico-chemical properties (infectivity, resistance to antiviral sera, partial sensitivity to the action of ribonuclease, sedimentation constants ranging between 80S and 160S, buoyant density in the Cesium gradient from 1.30 to 1.43 g/cc.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1972
Accession Number
AD0752190

Entities

People

  • A. S. Agabalyan
  • F. I. Ershov
  • L. V. Uryvaev.
  • V. M. Zhdanov

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acids
  • Amino Acids
  • Biomedical Research
  • Cells
  • Chemical Properties
  • Immune Serums
  • Incubation
  • Materials
  • Pharmaceutical Solutions
  • Probability Density Functions
  • Proteins
  • Ribonucleic Acids
  • Rna Viruses
  • Sedimentation
  • Sensitivity
  • Titration
  • Viruses

Fields of Study

  • Biology

Readers

  • Nuclear and Radiation Engineering.
  • Virology (or Medical Virology).