Regulation of Corticosteroid Synthesis and Secretion.
Abstract
The research has been directed toward two major problems: (a) localization and control of neurohumoral pathways in the brain which regulate pituitary release of ACTH and (b) the physiological mechanisms and biochemical factors involved in the control of adrenal steroid production. Of particular interest was the finding that slow (modulatory) and rapid (stress-induced) elevations in plasma corticosteroid levels may activate separate central mechanisms, possibly as a result of variations in thresholds to the activating stimuli. In addition, a scheme for a proposed interrelationship of the factors involved in the regulations of adrenocortical steroidogenesis is presented. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1972
- Accession Number
- AD0753051
Entities
People
- Sidney Roberts
Organizations
- University of California, Los Angeles