Analysis of Soluble Beryllium by Gas Chromatography
Abstract
A new microanalytical method for the detection and quantitation of beryllium in aqueous samples and biological specimens has been developed. The method, based upon quantitation of chelated beryllium by gas chromatography, was employed to detect beryllium in both in vitro samples and tissues of rats given beryllium by injection. Beryllium was administered in the form of aqueous solutions of beryllium sulfate, and as little as 10 nanograms beryllium per gram of whole blood were detected and quantitated. In vivo studies which compared gas chromatographic analyses with radiometric analyses confirmed the validity of the new microanalytical technique. Preliminary studies were conducted to determine the ability of fluorinated chelating agents to remove beryllium oxide from the lungs of rats.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1972
- Accession Number
- AD0753112
Entities
People
- Eugene L. Arnold
- Michael L. Taylor
Organizations
- Monsanto