Comparative Studies of Plaque Variants Derived from a Florida Strain of Venezuelan Equine Encephalomyelitis Virus
Abstract
Small- and large-plaque variants of a Florida strain (Fe 3-7c) of Venezuelan equine encephalomyelitis virus were studied in vivo and in vitro. The small-plaque variant was less virulent in mice, hamsters, and guinea pigs than the large-plaque variant. The variants could be distinguished by calcium phosphate chromatography. The implications of plaque variants within a mixed virus population are discussed.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 09, 1972
- Accession Number
- AD0753318
Entities
People
- Carl E. Pedersen Jr.
- David M. Robinson
- Donald R. Slocum
Organizations
- United States Army Medical Research Institute of Infectious Diseases