Neurochemical Changes in Specific Regions of Rat Brain During Different Phases of Conditioning,

Abstract

The activity changes of RNA polymerase, choline acetyl transferase, acetylcholinesterase and monoamine oxidase in five brain areas were investigated in groups of water deprived rats trained to run for water reward, extinguished after training or retrained after extinction. Marked increases in RNA polymerase and choline acetyl transferase activities were observed in the hippocampus of the experimental animals. A pronounced increase in the activity of RNA polymerase was also found in the posterior hypothalamus of trained rats. No significant changes in the activities of the other enzymes tested were observed as a result of training. (Author)

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1972
Accession Number
AD0757324

Entities

People

  • George N. Catravas
  • H. Teitelbaum
  • W. L. Mcfarland

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

DTIC Thesaurus Topics

  • Acetylcholinesterases
  • Anatomy
  • Animals
  • Biological Sciences
  • Brain
  • Central Nervous System
  • Enzymes
  • Extinction
  • Hippocampus
  • Hypothalamus
  • Laboratory Animals
  • Nervous System
  • Training
  • Transferases

Fields of Study

  • Biology
  • Psychology

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Molecular Genetics
  • Neuroscience