Genetic Aspects of the Synthesis of Catecholamines in the Adrenal Medulla,
Abstract
Data relevant to genetic variation in the enzymes involved in the synthesis of the catecholamines is reviewed. The authors demonstrate that strain differences exist in the activity of the enzymes involved in the synthesis of the catecholamines in mice, that this variation has a genetic basis, and that differential regulatory mechanisms of the enzymes involved in catecholamine formation exists in different mouse strains and presumably, this variation also has a genetic basis. These findings are discussed in relation to adrenal medullary function, and the role such genetic differences may play in behavioral states is considered.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1973
- Accession Number
- AD0764066
Entities
People
- David A. Hamburg
- Jack D. Barchas
- Roland D. Ciarenello
- Seymour Kessler
Organizations
- Stanford University