Model of Skeletal Muscular Contraction.

Abstract

A model of skeletal muscular contraction is developed from a diverse group of previously published experimental results. The model attempts to describe the events which take place within a single sarcomere during contraction. Included in the model are a number of separate process models which are new. These include a model for calcium release and reabsorption by the longitudinal vesicles, a model for binding of calcium to troponin, a model for determining the active state from the amount of calcium bound to troponin, a model relating the active state to cross-bridge formation, a model for breakdown of cross-bridges, and a model relating the existing cross-bridges at any time to the active force they generate. The cross-bridges are referred to as the contractile component. The model is completed by a damping element and an elastic element in parallel with the contractile component and another elastic element in series. (Modified author abstract)

Document Details

Document Type
Technical Report
Publication Date
May 01, 1973
Accession Number
AD0764573

Entities

People

  • Peter Martin Klauss

Organizations

  • Stanford University

Tags

Fields of Study

  • Biology
  • Mathematics

Readers

  • Computational Modeling and Simulation
  • Exercise and Sports Science.
  • Toxicology/Environmental Toxicology