The Control of the Cardiovascular and Central Nervous System.
Abstract
Studies on the effects of acute myocardial ischemia and left ventricular function on the conscious dog provided evidence for a cardia-cardiac reflex during ischemia and that there is beat-to-beat involvement of the aortic nerve in the regulation of heart beat. Studies on the effects of alcohol, tetrahydrocannabinol and methadone on brain biogenic amines implicating serotonin in the soporific action of ethanol and additional findings indicated that the pineal gland is involved in ethanol preference in rats and hamsters. Tetrahydrocannabinol was found to block alcohol-induced withdrawal symptoms in mice. Studies on the effects of aging on calcium transport in cardiac sarcoplasmic reticulum indicated that aging and heat activated inhibitory factors, which decreased active calcium transport in cardiac sarcoplasmic reticulum, could be prevented by ATP and magnesium. Several studies suggested cold storage of vascular tissue results in a supersensitivity to norepinephrine due to a partial deplorization in the muscle membrane and that calcium may play a role in hypertension seen in genetic hypertensive rats. It was found that pentobarbital anesthesia increased 5-HT content in all brain areas. LSD-25 produced a significant reduction in 5-HT turnover in all brain areas except diencephalon. (Modified author abstract)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 31, 1973
- Accession Number
- AD0764832
Entities
People
- Arthur H. Briggs
Organizations
- University of Texas at Austin