The Relative Effectiveness of Fission Neutrons for Gastrointestinal Damage in Mice: Jejunal Crypt Stem Cell Survival
Abstract
Mice were unilaterally irradiated in either a fission neutron or gamma ray field at various dose rates. Jejunal crypt stem cell survival was analyzed by the multitarget single-hit survival model, which yielded excellent fitting survival curves. At the 1 percent survival level, gamma rays were found to be 20 percent more effective in destroying cells when delivered in a brief pulse of radiation than when delivered at lower dose rates (40 rads/minute or 250 rads/minute). Increased cell survival was not observed for low dose rate neutrons. Do values obtained were consistent with the findings of similar studies; however, survival curve intercepts were found to be lower than previous estimates.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1973
- Accession Number
- AD0764971
Entities
People
- G. H. Zeman
- R. E. George
- S. G. Levin
- S. R. Jones
Organizations
- Armed Forces Radiobiology Research Institute