Development of a Synthetic Polymer Burn Covering.
Abstract
High molecular weight (140,000) poly-epsilon-caprolactone has been made using a bulk polymerization process. Poly-epsilon-caprolactone has been laminated to collagen film. When applied to a wound, collagen side down, the laminate successfully stimulated early coagulation and a fibrin network developed. Poly-epsilon-caprolactone has been laminated to nylon velour. A flash burn technique was established. Ploy-epsilon-caprolactone in a solvent solution was applied directly to the burn. Techniques were established for making porous poly-epsilon-caprolactone films which can be laminated to continuous films. A systematic program of epsilon-caprolactone ploymerizations has been initiated to determine the optimum reaction conditions. Poly-epsilon-caprolactone has been successfully bonded to two structured materials and the laminate tested in vivo.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 15, 1973
- Accession Number
- AD0765341