Clotting Factors of Supernatant Plasma Following Cryoprecipitation.
Abstract
The supernatant plasma which remains after cryoprecipitation is a useful component for transfusion therapy. However, from prior studies it was unclear how well plasma clotting factors were preserved following cryoprecipitation. Coagulation factor assays were performed on fresh plasma, supernatant plasma after removal of cryoprecipitate and the same supernatant plasma following refreezing and thawing. Factor VIII and fibrinogen levels fall considerably after removal of cryoprecipitate, but there were also significant declines in factors V and VII. Refreezing and thawing the supernatant plasma had little effect on most clotting factors. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 28, 1973
- Accession Number
- AD0765465
Entities
People
- Gerald J. Roth
- James A. Eaton Jr.
- Kenneth I. Tobias
- Thomas A. Rudai
- William E. Kline
Organizations
- United States Army Medical Research Laboratory