Characteristics of Virion RNA of Venezuelan Equine Encephalomyelitis Virus
Abstract
Certain physico-chemical parameters of infectious RNA of the Venezuelan equine encephalomyelitis virus were determined. It was established that virion RNA sediments in sucrose gradient with sedimentation coefficient of 38-40 S. In fractionation of RNA in cesium sulfate density gradient, the RNA was found in one zone of 1.66 g/cc density. Electrophoresis of virion 40 S RNA in 3.5% agarose-polyacrylamid gel supplied additional information on RNA preparations, making it possible to determine the molecular weight of RNA, which, in several different experiments, varied within the limits of 4,000,000 and 4,300,000 daltons.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1973
- Accession Number
- AD0768503
Entities
People
- A. S. Agabalyan
- F. I. Yershov
- L. V. Uryvayev
Organizations
- United States Army Medical Research Institute of Infectious Diseases