Rejection Mechanisms in Corneal Transplantation.
Abstract
The report details efforts to characterize the transplantation antigens of the cornea as encountered in xenogeneic keratoplasty. Three protein factions have been isolated from the cornea. Each has been shown to possess transplantation antigen activity as demonstrated by its ability to induce a specific sensitization resulting in the accelerated destruction of a subsequent corneal graft. The antigenic fractions are also capable of stimulating the production of humoral antibodies. The relationship between the transplantation immunity and the antibody response will be discussed. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 15, 1973
- Accession Number
- AD0768868
Entities
People
- Ephraim Freidman
- Howard M. Leibowitz
Organizations
- Boston University