Evaluation of Group C Meningococcal Polysaccharide Vaccine in Marine Recruits, San Diego, California
Abstract
Group C meningococcal polysaccharide vaccine was well tolerated by 3, 018 vaccinated Marine recruits. The vaccine appeared to be group-specific since it prevented the acquisition of only group C meningococci. The vaccine stimulated a good hemagglutinating antibody response, but did not stimulate a complement fixing antibody response. One systemic illness of uncertain etiology, possibly vaccine related, was observed among the vaccines. That the vaccine affords protection against clinical disease was suggested when three cases of meningococcal disease of group C etiology developed in the nonvaccinated controls while none occurred among the vaccinated men of the study population.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 29, 1969
- Accession Number
- AD0769364
Entities
People
- Earl A. Edwards
- Leonard F. Devine
- Solon L. Rhode
- Thomas M. Floyd
- Willard E. Pierce