Thermal Balance of Men Under Atropine Therapy Wearing Chemical Protective Clothing

Abstract

In warm environments the use of atropine in the treatment of casualties from anticholinesterase agents presents a possible hazard because the inhibition of sweating by atropine may lead to a dangerous rise in body temperature. Recently it was shown that after a 2-mg dose of atropine sulfate the effects of a deficit in sweating could be avoided by artificial wetting the clothing. One objective was to test this concept when the dose was increased to 6 mg. At this dose and an indoor temperature of 41 deg C, an initial wetting of the clothing with a liter of water was sufficient to prevent an undue rise in body temperature for 3 hours whereas when the clothing was initially dry the body temperature rose at an unsafe rate. A second objective was to evaluate the efficiency of evaporative cooling from wet clothing as a fraction of the evaporative cooling required to balance the heat equation. The conclusions were as follows: The elevation of body temperature in men wearing the two-layer chemical protective assembly in consequence of the inhibition of sweating by atropine given for treatment of the effects of anticholinesterase agents can be prevented by artificial wetting of the clothing. The efficiency of evaporative cooling of clothed men decreases as the water content of the clothing increases.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1973
Accession Number
AD0770378

Entities

People

  • E. G. Cummings
  • F. N. Craig

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Army Personnel
  • Assembly
  • Body Temperature
  • Chemical Warfare Agents
  • Clothing
  • Energy Transfer
  • Environment
  • Enzyme Inhibitors
  • Equations
  • Heat Balance
  • Heat Energy
  • Heat Of Vaporization
  • Maryland
  • Physical Properties
  • Protective Clothing
  • Sweating
  • Thermal Insulation

Fields of Study

  • Medicine

Readers

  • Exercise and Sports Science.
  • Neurotoxicology
  • Thermal Physics or Thermal Science.