The Antiviral Action of Ribonuclease

Abstract

With the use of a model of the virus of Venezuelan equine encephalomyelitis, the inhibiting effect of a preparation of pancreatic ribonuclease on the accumulation and infectious and hemagglutinating activity of the virus, and interferon production in chicken embryo fibroblast culture were determined. Statistical processing confirmed a high degree of correlation in the suppression of all three types of activity. The mechanism of virus-inhibiting action of ribonuclease is discussed. The article includes two tables, two illustrations and a bibliography of 16 titles.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1970
Accession Number
AD0770903

Entities

People

  • F. I. Ershov
  • V. Yu. Urbakh

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Antiviral Agents
  • Arbovirus Infections
  • Biomedical Research
  • Cells
  • Central Nervous System
  • Culture Techniques
  • Infection
  • Intact Stability
  • Interferon
  • Materials
  • Nervous System
  • Nucleic Acids
  • Production
  • Proteins
  • Venezuelan Equine Encephalomyelitis
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Library and Information Science
  • Virology (or Medical Virology).