Development of a Synthetic Polymer Burn Covering.
Abstract
The report summarizes work performed from February 1, 1973 to January 31, 1974. Standard methods have been used to measure water vapor transmission rates through thin films. Young's moduli from 300 psi to 500,000 psi and % elongations at yield from 15% to 1% have been measured for skin and polylactic acid respectively. In vivo tests on fully excised sections of Sprague-Dawley rats have been used to evaluate polylactic acid film, nylon film, collagen, human skin, Epigard and laminates of poly-epsilon-caprolactone with nylon velour and collagen. Laminates of poly-epsilon-caprolactone with collagen readily adhered to full excision wounds, exudated build-up was not observed at the covering/wound interface and after four days a well-vasculated interface was observed. Poly-epsilon-caprolactone sprayed onto a charred flash burn controlled insensible water loss at normal levels for ten days. (Modified author abstract)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 31, 1974
- Accession Number
- AD0773971
Entities
People
- Arthur D. Schwope
- Donald L. Wise