Isolation of Protective Antigens from 'Plasmodium falciparum'.

Abstract

An in vitro culture system for Plasmodium falciparum involving initial maturation of parasites followed by subculture has been elaborated. Mean multiplication rates of about threefold are obtained after 48 hours and parasite morphology is satisfactory. This system offers a basis for demonstrating the inhibitory action of human and simian immune sera raised against P. falciparum and should therefore provide a means for identifying protective antigens from this malaria parasite. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1974
Accession Number
AD0774438

Entities

People

  • G. A. Butcher
  • G. H. Mitchell
  • Sydney Cohen

Tags

DTIC Thesaurus Topics

  • Immune Serums
  • Malaria
  • Maturation
  • Parasites

Fields of Study

  • Medicine

Readers

  • Parasitology and Pharmacology of Malaria.
  • Theoretical Analysis.