'In vitro' Effect of Adenine on Stored Canine and Human Blood.
Abstract
Human and dog red cells stored for six weeks in high concentrations of adenine equivalent to 25 or 50 mg/kg body weight were found to show decreased pH, P50, and diphosphoglycerate (DPG) levels comparable to other studies. A decrease in adenosine triphosphates (ATP) with storage was observed; however, there was a higher level with greater adenine doses indicating support of the ATP level by the adenine. No signs of toxic effects from the high adenine doses were observed. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 31, 1973
- Accession Number
- AD0775798
Entities
People
- Charles E. Shields
- Daniel E. Brooks
- David E. Meixner
- Garry C. Phillips
- Joseph F. Bratton
Organizations
- United States Army Medical Research Laboratory