Sequential Search of Optimal Dosages for Non-Interactive Repetitive Models: I. Unknown Intercepts.
Abstract
The problem of the sequential determination of optimal dosages is, studied for a non-interactive repetitive model. Each patient has its own optimal dosage. The dosage-logtoxicity regression lines are linear. Those of different patients have different unknown intercepts (slopes known). Bayes sequential adaptive procedures of search developed. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 15, 1974
- Accession Number
- AD0776195
Entities
Organizations
- Case Western Reserve University