Effect of Certain Antimetabolites and of Chloramphenicol on Conjugation of E. coli K-12,

Abstract

There is major interest in studying the role of processes of transfer of genetic information in bacteria -- conjugation, transformation, and transduction -- in the appearance and propagation of antibiotic-resistant forms of microorganisms. Many researchers have established that by means of the above genetic processes it is possible to transform strains of certain types of bacteria which are sensitive to antibiotics into antibiotic-resistant organisms. The authors studied the effect of chloramphenicol, 5-bromouracil (5-BU), and 8-azaguanine (8-AG) on the conjugation of E. coli K-12 on the transfer of genetic markers from the donor to the recipient.

Document Details

Document Type
Technical Report
Publication Date
Mar 11, 1974
Accession Number
AD0776744

Entities

People

  • I. I. Belousova
  • I. M. Tereshin

Organizations

  • National Air and Space Intelligence Center

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antimetabolites
  • Aza Compounds
  • Bacteria
  • Genetic Markers
  • Genetic Processes
  • Microorganisms
  • Pharmacologic Actions
  • Prokaryotes

Readers

  • Materials Science and Engineering.
  • Molecular Genetics

Technology Areas

  • Biotechnology