Physicochemical Methods of Analyzing Hygromycin B,
Abstract
Hygromycin B is an antibiotic which possesses anthelmintic properties; it is produced simultaneously with another antibiotic - hygromycin A - by a strain of Str. hygroscopicus. Hygromycin B contains two groups of a basic character. In connection with this the separation of hygromycin B from the accompanying antibiotic can be carried out by sorption on cationites with subsequent desorption with aqueous or water-acetone solutions of ammonia or by dilute solutions of acids. To provide rapid evaluation of antibiotic concentration in solutions, the authors made an effort to develop adsorption-spectrophotometric methods of analyzing the antibiotic, working on the basis of the physicochemical properties of the antibiotic and its structural peculiarities.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 26, 1974
- Accession Number
- AD0776918
Entities
People
- A. P. Bashkovich
- N. S. Redi
Organizations
- National Air and Space Intelligence Center