PH Effects on Chloroform Extraction of Drugs of Abuse from Urine.

Abstract

The optimum pH for the single chloroform extraction of barbiturates and amphetamines was determined using radiolabelled drugs. Over the pH range 7.5-8.5, extraction of phenobarbital and amphetamine from urine into chloroform varied widely. The extraction of pentobarbital was much less affected by pH. For a single extraction of these drugs into chloroform, pH should be maintained at 8.0-8.2. (Author)

Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1974
Accession Number
AD0777899

Entities

People

  • George D. Lathrop
  • James H. Merritt
  • Thomas S. Sulkowski

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

DTIC Thesaurus Topics

  • Anesthetics
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Chloroform
  • Extraction

Readers

  • Analytical Chemistry
  • Child and Adolescent Substance Abuse Science in Autism Spectrum Disorders.