Effect of Polyene Antifungal Antibiotics on Glycolysis in Animal Tissues,

Abstract

According to literature data certain polyene antibiotics inhibit glycolysis in the bacterial and yeast cell. Polyene antibiotics also have a strong toxic effect on the animal organism. In connection with this the question arises of clarifying the effect of antibiotics on metabolism in the living organism. For this purpose a study was made of the effect of polyene antifungal antibiotics - the sodium salt of nystatin, pentaene 1454/69, and hexaene 868/9 - on glycolysis in brain tissue and erythrocytes.

Document Details

Document Type
Technical Report
Publication Date
Apr 18, 1974
Accession Number
AD0778530

Entities

People

  • V. N. Lutvinova

Organizations

  • National Air and Space Intelligence Center

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Cells
  • Erythrocytes
  • Fungi
  • Glycolysis
  • Literature
  • Metabolism
  • Nystatin

Readers

  • Battery Technology and Engineering
  • Oncology (Cancer Research).
  • Toxicology/Environmental Toxicology