Study of the Reaction Mechanism of Blood Neutrophils to Antigen,
Abstract
The increased sensitivity of neutrophils to allergen is realized against the background of quantitative shifts in the enzyme composition of cells and is the consequence of the appearance of the specific antigenic complexes in the organism. The reaction of neutrophils to allergen begins from the intense amoeboid activity, which subsequently is accompanied by subcellular degenerative changes. The conditions of manifestation of sensitivity to allergen (tuberculin) on the part of the blood neutrophils and outer integuments are ambiguous. Histamine in vitro does not cause the amoeboid reaction of the sensitized neutrophils and does not change its intensity during the incubation of blood with allergen.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 08, 1974
- Accession Number
- AD0779130
Entities
People
- V. A. Fradkin
Organizations
- National Air and Space Intelligence Center