Investigation of the Effect of Furacilin (Nitrofurazone) and Certain Antibiotics on the Development of 'Pen. nigricans Thom' and Extraneous Microflora in the Process of Griseofulvin Biosynthesis,
Abstract
In the entire process of production of biologicals the greatest attention is paid to measures which make it possible to carry out the technological process under sterile conditions. Laboratory experiments were carried out to determine the effect of various antibiotics and of furacilin (nitrofurazone) on the development of the griseofulvin producer and foreign microflora. The following antibiotics can be used for sterile fermentation of penicullium nigricans: levomycetin (10, 20, 40 units/mz), the potassium salt of penicillin (40, 60 units/mz), streptomycin (50 units/mz), and a mixture of penicillin and streptomycin, 50 units/mz each.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 15, 1974
- Accession Number
- AD0779275
Entities
People
- N. N. Mustafova
- T. V. Kozlova
Organizations
- National Air and Space Intelligence Center