Functional Role of Hypothalamic Histamine: Release of Vasopressin.

Abstract

Following the injection of histamine directly into the supraoptic nucleus, a dramatic decrease in urine flow ensued. This oliguria, and the concomitant increase in urine concentration, reflect the release of vasopressin. This histaminergic effect could be inhibited by an antihistamine, but not an antinicotinic, antimuscarinic or adrenergic blocker. It is suggested that hypothalamic histamine plays an important role in the release of vasopressin. (Author)

Document Details

Document Type
Technical Report
Publication Date
May 01, 1974
Accession Number
AD0779410

Entities

People

  • C. Thomas Bennett

Tags

DTIC Thesaurus Topics

  • Amines
  • Anatomy
  • Biological Sciences
  • Biomolecules
  • Brain
  • Central Nervous System
  • Chemical Compounds
  • Histamine
  • Hormonal Preparations
  • Hormones
  • Pituitary And Hypothalamic Hormones And Analogues

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Neuroscience