Aldehyde Treatment of Cyanide Poisoning in Mice

Abstract

Eight aldehydes have been tested as therapeutic compounds for cyanide poisoning in mice. The most effective are glyoxal trimer and glyceraldehyde. These increase the LD50 2.5 to 3 times. No correlation was found between activation of the carbonyl group resulting from nearby electron-withdrawing substituents and therapeutic value.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1974
Accession Number
AD0779540

Entities

People

  • George M. Steinberg
  • Norman C. Thomas

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aldehydes
  • Animals
  • Aqueous Solutions
  • Chemical Warfare Agents
  • Electrons
  • Equations
  • Governments
  • Laboratory Animals
  • Maryland
  • Observation
  • Organic Compounds
  • Poisoning
  • Preventive Medicine
  • Pyruvates
  • Pyruvic Acid
  • Security
  • Sodium Compounds

Fields of Study

  • Biology
  • Chemistry

Readers

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  • Environmental Engineering.
  • Organic Chemistry

Technology Areas

  • Microelectronics