Dry Live Aerosol Anthrax Vaccine

Abstract

In preparing the dry live aerosol anthrax vaccine the use of a spore culture of the STI-1 single vaccine strain and culturing of the latter on a solid medium in the AKMSh has considerably simplified the culturing process and ensured large amounts of spore culture obtained with a concentration of up to 10 billion spores in 1 mm of wash. Dry live aerosol anthrax vaccine is suitable for aerosol immunization if the calculated aspiration dose, when spraying the weighted quantity of the vaccine at 0.05 g for 1 cu m of the building by the PAV-65 device, is at least 1 mg. For a prolonged storage of the viable spores in dry live aerosol anthrax vaccine, it is necessary to store it under deep vacuum (in the range of 100-150 microns) and at temperatures not exceeding +10 degrees.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Apr 18, 1974
Accession Number
AD0779661

Entities

People

  • A. P. Budak
  • N. I. Aleksandrov
  • N. Ye. Gefen
  • O. A. Budneva
  • Yu. P. Nikolaenko

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aeration
  • Aerosols
  • Air Force
  • Air Force Facilities
  • Culture Techniques
  • Dispersions
  • Foreign Technology
  • Immunization
  • Military Medicine
  • Standards
  • Translations
  • Vaccines
  • Word Processors

Readers

  • Aerosol Science/Aerosol Physics
  • Immunology

Technology Areas

  • Biotechnology