Excretion of Minerals and Nitrogen Metabolites Following Exposure to Increased Air Pressure (2 or 7 ATA)
Abstract
Urinary minerals, electrolytes, nitrogen metabolites and steroids were measured in Navy divers following exposure to air at 2 and 7 ATA for 45 minutes. Total urinary excretion of osmoles, sodium, potassium, calcium, phosphorus, urea nitrogen, uric acid, creatinine, keto- and ketogenic steroids were depressed below control values during the first day following exposure to either 2 or 7 ATA. The mineral and electrolyte changes are related to reduction in urine volume which may result from an anti-diuretic hormone (ADH) mediated response to hypovolemia induced by dysbaric stress. Although a general rebound effect began to occur by the second post-dive day, a continued depression of uric acid, creatinine, and ketosteroids throughout four days of observation suggests a prolonged period of recovery from diving. Increasing excretion of hydroxyproline for several days by those men exposed to 7 ATA, implies a latent response in the metabolism of cartilage and bone to this stress.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 10, 1973
- Accession Number
- AD0780093
Entities
People
- Donald V. Tappan
- Elly Heyder
Organizations
- Naval Submarine Medical Research Laboratory