Development of Mosquito Repellents Having Increased Protection Time in Man.
Abstract
Synthetic topical repellents were prepared, following previously reported leads that resulted from intrinsic repellency studies and from Stanford Research Institute (SRI) computed-coded USDA compounds. The most promising structural area for topical repellency continues to be glycol ether derivatives, although the carbamide, 2,4-thiazolidinedione, and quinoxaline areas are also of interest. Efforts were directed toward polymer formulations of SRI glycol ethers to improve their wash-off characteristics and cosmetic acceptability. These studies range from the typical film-formers to carbowax stick-type formulations. Large samples of two 2,4-thiazolidinediones were synthesized for toxicologic evaluation. (Modified author abstract)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 15, 1974
- Accession Number
- AD0780117
Entities
People
- H. C. Tong
- Howard L. Johnson
- W. A. Skinner
Organizations
- SRI International