Effect of Storage on Oxygen Transport in Blood Obtained from Man, Dog and Monkey.
Abstract
Red cells obtained from human, monkey and canine subjects were stored in acid-citrate-dextrose (ACD) over a six week period and periodically tested for mid saturation point (P50), pH, adenosine triphosphate (ATP) and 2,3-diphosphoglycerate (DPG) levels. In addition, blood obtained from dogs kept chronically anemic and also from those undergoing daily exercise was stored and compared to the other groups. The anemic and exercised groups were found to have higher than normal DPG values, with only the exercise group showing corresponding elevation in P50 levels. The results showed a general decrease in all tested values with storage. (Modified author abstract)
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 16, 1974
- Accession Number
- AD0781498
Entities
People
- Angelo I. Zegna
- Charles E. Shields
- Daniel E. Brooks
- David E. Meixner
- Joseph F. Bratton
Organizations
- United States Army Medical Research Laboratory