Radiation Induced Changes in Intracranial Pressure and Arterial Blood Pressure

Abstract

Twenty Macaca mulatta monkeys were exposed to cobalt-60 gamma radiation at the rate of 1000 rad/minute for mid-thoracic doses of approximately 1307 rad to 10 monkeys and 2244 rad to the remaining 10 animals. The average intracranial pressure increased in both groups following exposure, but the response observed in the low-dose group was not so great as that elicited in the monkeys that were exposed to higher levels of irradiation. Hypotension developed in the majority of animals postirradiation, and the degree of response was greatest in the high-dose group of monkeys.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1974
Accession Number
AD0783794

Entities

People

  • John W. Watters
  • Louis F. Wailly
  • Peter B. Carter

Organizations

  • United States Air Force Academy

Tags

Communities of Interest

  • Energy and Power Technologies
  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Air Force
  • Animals
  • Arteries
  • Behavioral Sciences
  • Blood
  • Blood Vessels
  • Brain
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cerebral Edema
  • Dosimetry
  • Fluids
  • Gamma Rays
  • Laboratory Animals
  • Measurement
  • Radiation
  • United States

Readers

  • Cardiovascular Physiology
  • Nuclear and Radiation Engineering.
  • Toxicology/Environmental Toxicology