Serological Diagnosis of Gonorrhea.
Abstract
An antigen has been extracted from T1 phase of Neisseria gonorrhoeae which has been characterized very crudely as a nucleoprotein. Preparations of this antigen were labeled biosynthetically with 14C and used in a radioassay for serodiagnosis of gonorrhea in humans. The results of the assays with this antigen may be summarized as follows: 90% of male and 98% of female sera were correctly diagnosed as positive (combined 93% correct); 32% of male and 82% of female sera were correctly diagnosed as negative (combined 60% correct); 5% of male and 2.5% of female sera could not be assigned positive or negative values. Preliminary results with an 125I labeled gonococcal antigen were similar to those described above. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 31, 1974
- Accession Number
- AD0784404
Entities
People
- Jon A. Rudbach
- M. Kay Luoma
- William R. Cross
Organizations
- University of Montana