Experimental Study of the Effect of the Dose of a Chemical Substance on the Incidence and Intensity of Contact Allergy,

Abstract

A direct relationship exists between the dose of a chemical allergen and the intensity of contact allergy. In a large number of chemical allergens, the threshold of allergizing action is below the threshold of toxic action during absorption through the skin. On this basis when setting permissible standards it is not necessary to consider the specific effect. Certain weak allergens can be active sensitizers even in toxic doses.

Document Details

Document Type
Technical Report
Publication Date
Aug 21, 1974
Accession Number
AD0785210

Entities

People

  • A. S. Raben
  • L. A. Dueva
  • O. G. Alekseeva
  • S. G. Barlogova
  • Sh. Z. Zagidullin

Organizations

  • National Air and Space Intelligence Center

Tags

DTIC Thesaurus Topics

  • Absorption
  • Allergens
  • Allergic Diseases
  • Antigens
  • Intensity
  • Standards
  • Toxic Actions

Fields of Study

  • Physics

Readers

  • Allergy and Immunology.
  • Environmental Engineering
  • Nuclear and Radiation Engineering.