Technical Manual for Identification of Hemoglobin Variants and Deficiency of Glucose-6-Phosphate Dehydrogenase.
Abstract
The manual of laboratory methodology was developed to provide basic information for testing programs for two genetic characteristics, variant hemoglobins and deficiency of glucose-6-phosphate dehydrogenase (G6Pd). The first section describes the approach to be used for voluntary programs primarily concerned with genetic counseling. In these programs, individual patients will generally request medical advice on the mode of inheritance of abnormal hemoglobins and the consequence of their hemoglobin phenotype on possible children. It must be emphasized that these programs are strictly voluntary and require electrophoresis as the primary laboratory method. The second section deals with testing of all entering military personnel for the purposes of industrial health safety. In this program, all persons entering on active duty are tested by automated techniques for the presence of hemoglobin S and/or deficiency of erythrocyte G6PD. (Modified author abstract)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1973
- Accession Number
- AD0787494
Entities
People
- C. E. Brodine
- D. E. Uddin
- L. G. Dickson
Organizations
- Naval Medical Research Center