COCCIDIOIDIN SENSITIVITY ELICITED IN GUINEA PIGS BY REPEATED SKIN TESTING,

Abstract

Delayed hypersensitivity was elicited in guinea pigs by repeated skin testing with potent coccidioidin. Characteristics of delayed hypersensitivity were evident upon gross and microscopic observations. Skin testing with basal medium produced reactions that were grossly negative at 24 and 48 hours and that differed microscopically by the intensity of the reaction and the more rapid resolution. No immediate anaphylactic reaction was produced by intracardiac injection of potent coccidioidin. (Author)

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1966
Accession Number
AD0800593

Entities

People

  • James T. Sinski

Tags

DTIC Thesaurus Topics

  • Allergic Diseases
  • Anaphylaxis
  • Diseases And Disorders
  • Hypersensitivity
  • Immune System Diseases
  • Intensity
  • Observation
  • Rodents
  • Sensitivity

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology
  • Materials Science (Mechanical Engineering).