PINOCYTOSIS, ZEIOSIS, AND INTERCELLULAR INTERCHANGE IN TISSUE CULTURES.
Abstract
This project was initiated to develop new insights and perspectives on membranes of vertebrate cells cultivated in vitro. The three approaches to this analysis involved observations on the membrane as it underwent ruffling processes and engulfed fluid droplets (pinocytosis), a blebbing activity which occasionally was observed to be involved in a similar fluid intake (zeiosis), and interactivities of cells which might involve intercellular exchanges of cytoplasmic components. The largest accumulation of information has involved the activity of zeiosis. These studies have been useful in developing a major new technique for cell culture. This technique will be described as the Circumfusion System. It has been proved as one in which its artificial environments are conducive for the maintenance of differentiated tissues. With this system it is expected that a more unified understanding of the cell membranes' functions and requirements in their contributing role to these basic units of life will be found.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 30, 1966
- Accession Number
- AD0803468
Entities
People
- George G. Rose