ON THE COOPERATIVITY OF BIOLOGICAL MEMBRANES.

Abstract

We extend the Monod-Wyman-Changeux of allosteric transitions in enzyme-substrate reactions to a membrane composed of identical units (protomers). It is supposed that each protomer can exist in two states. The interaction between protomers is treated in the molecular field approximation. It appears possible to have a first-order phase transition when the chemical potential of the substrate is varied, holding the temperature constant. The wide range of possible biological implications is discussed. (Author)

Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1966
Accession Number
AD0804282

Entities

People

  • C. Kittel
  • Jean Thiery
  • Jean-pierre Changeux
  • Yvonne Tung

Organizations

  • University of California, Berkeley

Tags

DTIC Thesaurus Topics

  • Critical Temperature
  • Glass Transition Temperature
  • Membranes
  • Phase Transformations
  • Substrates
  • Transition Temperature
  • Transitions

Fields of Study

  • Physics

Readers

  • Mathematical Modeling and Probability Theory.
  • Molecular Genetics
  • Molecular and Cellular Biochemistry