STUDIES ON THE COCCIDIUM, EIMERIA TENELLA,

Abstract

Essentially pure sporulated Eimeria tenella oocyst suspensions, suitable for experimental purposes, were obtained by shaking at 30 C homogenized infected chicken ceca in 2.5% potassium dichromate, digesting extraneous material with 3% KOH at 40 C (in the presence of fecal debris, with an additional incubation in 70% H2SO4), and further purifying by selective recovery from the aqueous phase of a chloroform-water suspension. A quantitative assay of infecting dose in chicks could be made by harvesting ceca (after 7 days) and counting total oocysts; oocyst viability could be determined by per cent in vitro excystation of sporocysts. Oocysts failed to survive freezing in liquid nitrogen or drying, but survived for short periods at -5 to -30 C. Ammonium hydroxide, aqueous iodine, and ethylene oxide were the only disinfectants found effective against E. tenella oocysts. Cross-infection studies with other animal species were uniformly unsuccessful. (Author)

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1966
Accession Number
AD0806775

Entities

People

  • Ernest M. Snyder
  • John L. Converse
  • John P. Kondig

Tags

DTIC Thesaurus Topics

  • Alkenes
  • Anti-Infective Agents
  • Chemical Compounds
  • Chloroform
  • Disinfectants
  • Ethylene Oxide
  • Ethylenes
  • Films
  • Freezing
  • Hydroxides
  • Incubation
  • Infection
  • Materials
  • Nitrogen
  • Potassium
  • Potassium Dichromate
  • Wound Infections

Readers

  • Analytical Chemistry
  • Immunology
  • Parasitology and Pharmacology of Malaria.