INTERFERENCE AMONG GROUP A ARBOVIRUSES

Abstract

An interference was observed among different strains of group A arboviruses that did not involve the participation of interferon. To act as an interfering agent, the first virus must be viable and must be inoculated either at a high multiplicity while the superinfecting virus is at a low multiplicity, or the first virus must have several hours' growth advantage in the host cell before superinfection by the second virus. The situation observed for these arboviruses appears to be very similar to that reported for poliovirus. The inhibition by interference might be due to direct competition within the host cell for substrate or replication sites.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1967
Accession Number
AD0807575

Entities

People

  • Arthur Brown
  • Eugene Zebovitz

Tags

DTIC Thesaurus Topics

  • Arbovirus Infections
  • Arboviruses
  • Biological Factors
  • Biological Sciences
  • Chemistry
  • Coinfection
  • Encephalitis
  • Equine Encephalitis
  • Infection
  • Inhibition
  • Interferon
  • Proteins
  • Substrates
  • Trinidad
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology
  • Radio communications and signal processing.
  • Theoretical Analysis.