A UNIQUE DEFENSE MECHANISM AGAINST ANTHRAX DEMONSTRATED IN DWARF SWINE

Abstract

A unique defense mechanism against Bacillus anthracis was demonstrated by the Pitman-Moore variety of dwarf swine. A large percentage of spores failed to germinate in vivo when massive doses were administered via either the respiratory or intraperitoneal route. Only spores with no apparent outgrowth of vegetative cells could be cultured from the blood. Therefore the defense mechanism enables the swine to prevent germination and outgrowth of B. anthracis spores in vivo.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1967
Accession Number
AD0809119

Entities

People

  • Frederick Klein
  • Jerry S. Walker
  • Ralph E. Lincoln

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Animals
  • Blood
  • Buildings And Structures
  • Cells
  • Defense Mechanisms
  • Infection
  • Laboratory Animals
  • Leukocytes
  • Lymph Nodes
  • Lymphatic System
  • Maryland
  • Mathematics
  • Research Facilities
  • United States
  • Wound Infections

Readers

  • Microbial Pathology
  • Trauma Surgery or Emergency Medicine.