NEIGHBORING GROUP EFFECTS IN PHOSPHONATE ESTER HYDROLYSIS I. NEIGHBORING CARBONYL GROUP IN PARA-NITROPHENYL PHENACYL METHYLPHOSPHONATE.
Abstract
Kinetic studies on the alkaline hydrolysis of p-nitrophenyl phenacyl methylphosphonate, 1-anthraquinonyl p-nitrophenyl methylphosphonate, and ethyl p-nitrophenyl methylphosphonate were carried out. The results clearly demonstrate the participation of the neighboring carbonyl group in markedly accelerating the alkaline hydrolysis of selected methylphosphonates. Mechanisms are offered as possible explanations of the rate of enhancement. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 1967
- Accession Number
- AD0812673
Entities
People
- Claire N. Lieske
- Edward G. Miller Jr.
- George M. Steinberg
- Gerald J. Zeger