THE RESULTS OF STUDYING THE BRUCELLA VACCINE FROM THE BR. ABORTUS 104-M STRAIN
Abstract
An experimental study of the vaccine strain of Br. abortus 104-M on guinea pigs supported its fine immunogenic properties during subcutaneous and cutaneous application, its ability to take and the ability to cause an active immunological reorganization. During experimental testing on sheep, vaccine from the Br. abortus strain 104-M turned out to be harmless in doses of 8--10 billion microbial cells, it survived for a sufficiently long time in the organism, and it created an immunity which was more intense than that of Br. abortus 19. On the farms where the sheep were treated with the vaccine from this strain a sharp reduction was noted in the number of abortions, there was an increase in the output of healthy young stock, and a significant lowering of morbidity with brucellosis among the persons who take care of these animals. Strain Br. abortus 104-M may be recommended for the prophylactic vaccination of sheep for the purpose of forming healthy livestock.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1966
- Accession Number
- AD0815200
Entities
People
- A. M. Polyakova
- I. F. Taran
- I. Zamakhayeva
- N. M. Nelyapin
- S. V. Abakin
Organizations
- United States Army Biological Warfare Laboratories