STUDIES ON ANTHRAX TOXIN PRODUCED IN VIVO
Abstract
Specific anthrax antigens were demonstrated in the blood of animals dying from anthrax. These antigens appeared in the blood when organisms were first detected and their concentration continued to increase as the concentration of organisms increased. These antigens did not elicit a strong anitbody response. In some respects, the toxin produced in vivo is different from that produced in vitro (may kill more rapidly, harder to detect lethal factor). The in vivo toxin also exists as an aggregate whose biological and serological activity depends upon its particular composition and/or configuration.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1967
- Accession Number
- AD0820846
Entities
People
- Donald C. Fish
- Ralph E. Lincoln