TRANSPORT OF MACROMOLECULES ACROSS BIOLOGICAL MEMBRANES.
Abstract
In general, it may be safe to assume that, for small molecules, the study of transport relations may become a study of the energy of transition between aqueous and lipid phase, but the multitude of forces may make an extremely complex analysis necessary. For the case of the macromolecule, even more complexity will be involved, since the disturbance of the membrane lattice may be much larger than that in the movement of small molecules. In the analysis of the mechanisms, forces and energies, the lipid bilayer membrane, and its modifications, should provide an important tool, to be used in conjunction with other tools, to accumulate specific information. In this role it may provide much information which could not be obtained by other means but it must be used judiciously, in full recognition of its problems as well as advantages. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 31, 1947
- Accession Number
- AD0821971
Entities
People
- R. C. Bean