PRESERVATION OF RED BLOOD CELLS BY FREEZING: THE RELATIONSHIP BETWEEN DIMENSIONAL PROPERTIES OF RED CELLS AND POSTTRANSFUSION SURVIVAL.
Abstract
No significant correlation exists between the mean corpuscular volume or the mean corpuscular hemoglobin concentration and posttransfusion survival of red cells frozen with addition of lactose 15%-dextrose 10% or modified with lactose solution followed by freezing with dextran or albumin. The correlation between dimensional properties of frozen red cells and their posttransfusion survival appears to be controlled by the procedure used for freezing cells. Similar results are shown from the study of red cells stored in the liquid state and made microcytic by addition of lactose, maltose and sucrose to ACD solution. The present work is part of a study of parametric in vitro determinations which may offer presumptive evidence of the viability of red cells stored in the frozen or liquid state. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 30, 1967
- Accession Number
- AD0824526
Entities
People
- Max M. Strumia