PATHOGENESIS OF PLAGUE: II. AN EQUIVALENT OF THE GENERALIZED SHWARTZMAN REACTION IN THE MONKEY
Abstract
Glomerular fibrin thrombi were observed in monkeys with both pneumonic and bubonic plague. Eighty per cent of animals in this study dying of pneumonic plague had glomerular thrombi. These findings are equivalent to those of the generalized Shwartzman reaction and suggest the possibility that endotoxin released from Pasteurella pestis during infection contributes to the pathogenesis of plague.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1967
- Accession Number
- AD0827092
Entities
People
- John J. Petery
- Milton J. Finegold
- Richard F. Berendt