GENETIC CONTROL OF VIRUS PRODUCTION IN CELL LINES

Abstract

A procedure to maintain genetic control during virus production in tissue cell lines is proposed and discussed. Both the tissue cell in which the virus product and the virus inoculum must be homogeneous in order to produce a virus with the replicates and the virus inoculum must be homogeneous in order to produce a virus with the expected characteristics. Certain philosophical and technical aspects of the problem are discussed in relation to developing and maintaining genetically homogeneous stock culture, inoculum, and product.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1968
Accession Number
AD0828768

Entities

People

  • Francis J. Weirether
  • Jerry S. Walker
  • Ralph E. Lincoln

Tags

DTIC Thesaurus Topics

  • Animal Diseases
  • Anti-Bacterial Agents
  • Arbovirus Infections
  • Bacteria
  • Cell Line
  • Cells
  • Environment
  • Genetic Variation
  • Genetics
  • Homogeneity
  • Materials
  • Particles
  • Production
  • Standards
  • Venezuelan Equine Encephalomyelitis
  • Virion
  • Viruses

Fields of Study

  • Biology

Readers

  • Immunology
  • Regression Analysis.
  • Systems Analysis and Design

Technology Areas

  • Biotechnology